Scientist Bioanalytics - High Res MS - Switzerland
15 March 2013
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Scientist Bioanalytics - High Resolution Mass Spec - Switzerland
You have experience in analytical chemistry, especially in the field of advanced mass spectrometry (high resolution MS, MS/MS) coupled with either liquid or gas chromatography (LC, GC). You are highly motivated and are ready to work independently within a dynamic and international work environment. You are always committed to deliver work of the highest quality and are comfortable handling multiple priorities with challenging timeliness whilst maintaining a high level of productivity.
The successful candidate will join the Complex Matrix Characterization & Metabolomics Group in the R&D Department and will perform method development and analysis in support of studies conducted to identify and quantify aerosol constituents and metabolites in biological matrices.
Specifically, you will:
Develop and apply high resolution LC-MS, LC-MS/MS and/or GC- MS methods for the screening of metabolites in biological matrices
Perform characterization, identification and quantitation of small molecules in complex matrices using classical and state-of-the-art mass spectrometric instrumentation
Perform non-targeted screening and apply metabolomics approaches on complex matrices
Identify metabolites and quantify adducts in biological matrices
Work in a team to prepare samples and generate scientific data
Maintain, operate and troubleshoot high resolution LC-MS, LC-MS/MS and/or GC- MS instruments and other analytical equipment
Write Standard Operating Procedures (SOPs), research protocols, study plans and study reports
BSc or MSc in chemistry, analytical chemistry, biochemistry or equivalent
Three to five years of hands-on experience in bioanalytical method development, validation and sample analysis using LC- and/or GC- mass spectrometric techniques
Practical experience in advanced mass-spectrometric techniques using high resolution MS (Orbitrap, QExactive), GCxGC-TOF, GC/LC-MS/MS with a primary focus on advanced LC-MS techniques
Practical experience of mass-spectrometric targeted and non-targeted screening techniques
In-depth knowledge of LC- and/or GC-MS techniques and sample preparation is essential
Mass-spectrometric software and database management skills
Significant experience with the development of study protocols, SOPs, validation and analytical reports
Well-developed communication skills, problem solving skills, creative thinking as well as the will to be a team player
Fluency in spoken and written English
This is a fantastic opportunity to join a global company. In return the company are offering an extremely competitive salary and an excellent benefits package including pension, healthcare and a generous relocation package where applicable. For further information on this superb opportunity please feel free to contact myself, Lauren Gripton of Paramount Recruitment, on +44 (0) 121 616 3465.
Analytical chemistry, LCMS, high res, high resolution, GCMS, LC-MS, LC/MS, GC-MS, GC/MS, mass spec, bioanalyst, scientist, BSc, MS, biological, metabolites, method development, method validation, orbitrap, Qexactive, tof, sample preparation, chemisty, chemist.
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